Profhilo vs Sunekos. A practitioner comparison.
Both Profhilo and Sunekos 200 are positioned as bio-stimulators, both ship in 2ml-class formats, and both target skin quality rather than volumising. Beyond that, the mechanism, protocol and indication differ materially. This is the comparison most aesthetic-clinic owners need before deciding stock-mix.
Mechanism
Profhilo is hybrid hyaluronic acid (high and low molecular weight HA cross-linked) by IBSA. The active mechanism is HA-driven hydration plus a bio-remodelling effect on collagen and elastin. Five-bolus BAP technique.
Sunekos 200 is HA combined with six amino acids (glycine, L-proline, L-lysine, L-leucine, L-valine, L-alanine) by Professional Derma. The active mechanism is fibroblast bio-stimulation; the amino-acid load functions as a substrate for collagen and elastin synthesis.
Indication overlap and difference
| Dimension | Profhilo | Sunekos 200 |
|---|---|---|
| Primary indication | Skin laxity, face, neck, decolletage | Bio-stimulation, periorbital, perioral, neck |
| Mechanism | Hybrid HA bio-remodeller | HA plus amino-acid fibroblast substrate |
| Protocol | 2 sessions, 30 days apart | 3 sessions, 14 days apart |
| Pack | 1 pre-filled syringe, 2ml | 2 vials, 3ml each |
| OFAB trade price | EUR 89.43 ex VAT | EUR 97.56 ex VAT |
| Best for | Adult skin-quality maintenance | Periorbital, fine-line, fibroblast targeting |
When to choose Profhilo
- Patient presents with skin laxity in face, neck, or decolletage.
- Maintenance protocol for adult skin quality.
- Two-session timeline preferred over three.
- HA-bio-remodelling-first practitioner preference.
When to choose Sunekos 200
- Periorbital indication (Profhilo is not the first-line periorbital choice).
- Patient with fine lines and fibroblast-substrate need.
- Three-session protocol acceptable.
- Fibroblast bio-stimulation framing fits the patient conversation better than HA bio-remodelling.
When to layer both
The combined Profhilo plus Sunekos protocol is increasingly standard in Irish premium clinics. The two products work via separate mechanisms, so layering does not double-dose a single pathway. A typical sequence is Sunekos 200 (three sessions, fibroblast bio-stimulation) followed at week eight by Profhilo (two sessions, HA bio-remodelling). This is a six-month treatment plan rather than a single-product protocol; price the patient accordingly.
The mistake most clinics make is positioning Profhilo and Sunekos as substitutes. They are complements. Pricing them as a layered protocol unlocks a higher patient lifetime value than either alone.
Stock implication for the clinic
If you are stocking one, Profhilo gets the larger budget because the Irish patient-recognition is higher; Sunekos converts on the practitioner recommendation rather than the brand pull. If you are stocking both, hold a 60/40 ratio Profhilo to Sunekos by unit count. Adjust based on six-month patient-mix data.
Order links
Both products are in stock at Coolock and dispatch same day on weekday orders before 12:30. View Profhilo or view Sunekos 200. Trade pricing is released after practitioner verification.